(3S)-3-[[(Phenylmethoxy)carbonyl]amino]-1-piperidinecarboxylic acid tert-butyl ester - Names and Identifiers
(3S)-3-[[(Phenylmethoxy)carbonyl]amino]-1-piperidinecarboxylic acid tert-butyl ester - Physico-chemical Properties
Molecular Formula | C18H26N2O4
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Molar Mass | 334.41 |
Density | 1.15 |
Boling Point | 471.6±44.0 °C(Predicted) |
pKa | 12.05±0.20(Predicted) |
Storage Condition | 2-8°C |
(3S)-3-[[(Phenylmethoxy)carbonyl]amino]-1-piperidinecarboxylic acid tert-butyl ester - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
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HS Code | 29333990 |
(3S)-3-[[(Phenylmethoxy)carbonyl]amino]-1-piperidinecarboxylic acid tert-butyl ester - Introduction
(S)-1-Boc-3-(Cbz-amino)-piperidine is an organic compound with the chemical formula C17H24N2O3. It is a white crystalline solid, stable at room temperature. The compound has a certain toxicity, should avoid contact with the skin and inhalation.
(S)-1-Boc-3-(Cbz-amino)-piperidine is commonly used in organic synthesis, especially as an important intermediate in drug synthesis. It can be used to synthesize other ligands or compounds for the synthesis of new drug molecules. It can also be used as a catalyst and expansion agent.
The method for preparing (S)-1-Boc-3-(Cbz-amino)-piperidine can be achieved by introducing an N-protecting group (Boc) and a C- protecting group (Cbz) into piperidine. One common method is by reacting piperidine with methyl chloroformate to form N-formylpiperidine, which is then reacted with ethyl 2-chloroacetate to form the (Cbz) amino group.
When using or handling (S)-1-Boc-3-(Cbz-amino)-piperidine, pay attention to proper laboratory practices and wear appropriate protective equipment, such as gloves and safety glasses. Keep away from open flames and heat sources, and avoid inhalation or direct skin contact. Waste generated during disposal shall be disposed of in accordance with local regulations.
Last Update:2024-04-09 02:00:40